Some information about the COVID-19 vaccines currently being distributed.

edited December 2020 in General

A couple of days ago I had the opportunity to attend a Zoom meeting with Dr. Barney Graham, an immunologist working at the NIH who helped develop the COVID-19 mRNA vaccines that are currently being distributed by Pfizer and Moderna.

We all have questions about these vaccines, so I want to share a few things I have learned.

Both mRNA vaccines are very similar and had similar results in trials. The vaccines are 94-95% effective in preventing infection and symptoms of COVID-19, but it is still possible to transmit the virus having received the vaccine, but it is about 3X less likely. The full effect of the vaccine occurs about 10 days after the 2nd dose.

Of the 4-5% of study participants that contracted COVID-19 after receiving two doses of the vaccine, none of them experienced serious symptoms that required hospitalization. In other words, even if you are unlucky enough to be one of the people for whom the vaccine does not prevent infection, there is no evidence that you will experience symptoms worse than a bad cold.

The vaccine is given in two doses, 3 and 4 weeks apart for Pfizer and Moderna, respectively. A second dose is reserved for everyone who gets the first dose to guarantee availability.

You have about 20% chance of experiencing flu-like symptoms after the 2nd dose. This is your body’s immune system reacting to the vaccine. The reaction is more likely in younger adults than older. The symptoms are short lived, going away after a couple of days.

There are two ways to develop immunity to Covid-19, neither of which are guaranteed to be 100% effective for the long term.
1. Getting the virus through exposure, and surviving it.
2. A vaccine.
The vaccine is the preferred way to get immunity because one of the possible effects of COVID-19 is death.
No one who had been vaccinated with with mRNA vaccine has died. The CDC is currently tracking every person who gets the vaccine to monitor symptoms as it rolls out to the public.

Originally I was hesitant to receive the vaccine, but now that I know more, I will be getting in line for it as soon as I am allowed to do so.

Below is a link to Dr. Graham’s bio, and also a link that provides more answers to common questions about the vaccine that I recommend reading.

I’m providing this information for the benefit of the cuddling community. I don’t work for Pfizer or Moderna, and I don’t own stock in them. I do not dictate public policy and I’m not affiliated with any political or special interest groups. I am not dictating your behavior and you can make your own decision if you decide to get the vaccine or not.

https://www.niaid.nih.gov/research/barney-graham-md-phd

https://ideas.ted.com/the-top-7-covid-19-vaccine-questions-answered/?utm_source=recommendation&utm_medium=email&utm_campaign=explore&utm_term=ideas-blog-3

Comments

  • Great post, thank you.

  • edited December 2020

    @MrPaul You have incorrect information posted. You do not get immunity from having had Covid-19 and surviving it. In fact they are finding the antibodies from surviving Covid to be short-lived. The NIH and the CDC are saying to get the vaccine even if you have had Covid before.

  • I second @FunCartel post. Herd immunity is not effective with this virus. That has been confirmed.

  • @FunCartel @ScrantonCuddler There have been at least two confirmed cases where a person contracted COVID-19 twice. One case was determined to be a mutated strain that was different enough from the original to constitute a separate virus. The 2nd one was thought the be the result of a false negative. However, I agree that a vaccine is the better option by far.

    In either case, COVID-19 or vaccine, we do not know how long immunity will last. By taking the path of an aggressive vaccination program we stand a good chance of stopping the pandemic.

    Can you please point me to the source of your information so I can do more research. Meanwhile I have updated my post to add more clarity. The information I presented came from the presentation by Dr. Graham.

  • @FunCartel @ScrantonCuddler To my understanding, I have heard of rare cases where someone has gotten COVID-19 twice.
    However, I wouldn't jump to conclusions and say herd immunity is not effective with this pandemic.

    There are many sources that support the fact that many people DO develop antibodies after experiencing COVID-19, and these help protect them from COVID-19 for a significant duration of time afterwards.

    This particular article says it may be around 5-7 months, some longer potentially:

    https://www.healthline.com/health-news/how-long-does-immunity-last-after-covid-19-what-we-know#What-we-currently-know-about-COVID-19-immunity
    (From October 14, 2020)

  • Also really great information, thanks @MrPaul ! This is exciting :)

  • Thanks @MrPaul. My sister works for Pfizer and is super proud right now. I don't mind the social distancing lifestyle I'm doing and I'm undecided about getting the vaccine, so waiting and watching and will do whatever it is I do when I do it.

    I appreciate the risks that I know Pfizer took to develop and manufacture this vaccine.

  • I am a nurse and know of several patients personally who have contracted covid 19 twice. The immunity from getting the virus is around 3 months. I would imagine there are a lot more who have had it twice than I personally know.

  • @cuddleanurse If we assume that getting Covid-19 does not guarantee immunity, then the vaccine will be our only hope. The recommendation in that case is for everyone to receive a vaccine. I believe the presentation I saw said the vaccine continued to provide effective protection for over 6 months, as measured by antibody levels.

    As I understand it the mRNA is programmed to make proteins that bind to the crown part of the virus, the spike, to prevent it from penetrating the cell wall. It could be a stronger and more universal defense than natural antibodies, which could be tripped up if the virus mutates. I’m assuming the viral spike protein is common among mutations of the virus, which may or may not be the case. I’m not an expert in this field by any means, I’m just thinking that the virus needs the same key to open the cell, so it needs to be invariant.

  • @cuddleanurse, you are spot on! I work in a dedicated COVID only hospital, and we are seeing more and more patients that are on their second time of having the virus.

    @MrPaul, I received my first round of the vaccine Thursday morning. I am high risk due to health issues, so I decided to go ahead and give it a go.

  • @cuddleanurse @MelanieL same here , I have seen several readmits as well as readmits for issues related to prolonged symptoms even though are now testing negative

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