OxyContin vs Oxytocin

xandriarainxandriarain
in General

I am really enjoying the show "Dopesick" on Hulu. The show is about OxyContin when it first was released in the 90s/ early 2000s and how the Purdue pharma reps sold the drug to doctors and hospitals. So I want to play a game where we pretend to be sales reps for Cuddle Pharma and hear your best sales pitch for Cuddle Sessions/ Oxytocin. You are allowed to stretch the truth or even lie a little, you are a big pharma rep after all. Let's outdo Purdue pharma and convince Doctors to prescribe cuddle sessions rather than OcyContin. You can also compare Oxytocin to other types of drugs such as psych meds and convince psychiatrists why cuddling is superior.

Comments

  • [Deleted User]Saysoh (deleted user)

    Man, I'm not sure where to go with this, yea? Are you saying cuddling relieves chronic pain, bipolar, chronic depression and anxiety? Kind of a stretch I think.

  • Chris04Chris04
    edited October 2021

    Wait. We talking bout Apple and Oranges.
    Oxytocin you can naturally get by human touch in which will last in the system over day.
    And OxyCotin. Is just another drug makes you feel good. Will last in the system up to certain hours.

    Lot of drugs will boost dopamine by an excess
    ( dopamine, one the 4 main happy n feel good hormones- Oxytocin. Endorphin, dopamine, Serotonin )
    Thsts where drug addiction comes in ......

  • [Deleted User]CharlesThePoet (deleted user)

    I'm confused.

    Isn't that game already being played on this website, and in innumerable professional profiles?

  • [Deleted User]Saysoh (deleted user)

    @Chris04

    Actually, you shouldn't generalize addiction to the reward system. There are substances the body gets physically addicted to: Benzos, Opiates, Alcohol. Nobody gets physically addicted to meth, MDMA, weed.

    Also, you should drop, "drug," from addiction, because people get addicted to alot of things- food, porn, sex, technology, sugar all of which are just as damaging mentally and physically. Sugar is actually worse than alcohol.

  • Chris04Chris04

    @Saysoh Wait wait wait....
    Lot of the things you mentioned, it Literally boost dopamine. Even the none drugs addiction thy boost dopamine.
    We has humans want to feel good. ( dopamine been one of the main feel good hormones) thats why people get addicted to basically every thing you mentioned.

  • [Deleted User]ernesto_2 (deleted user)

    @Chris04 what @Saysoh was trying to say was that drug abuse is not limited to an abuse of our reward system. There are both physiological and psychological addiction, and likewise both physiological and psychological indicators of addition.

    The point being that addiction is not bound to "feeling good".

  • calmcontactcalmcontact
    edited October 2021

    Not to be a real nerd (I am a nerd and am studying cognitive science), but Oxytocin is generally the subject of a lot of misconceptions and/or oversimplification.

    Did you guys know that it can actually be a stress hormone and that the way it regulates our behavior can be very different depending on whether we feel safe with present company or not?

    Here's one article that goes into a little more detail on this.
    "The two faces of oxytocin"
    https://www.apa.org/monitor/feb08/oxytocin

    Reducing oxytocin down to the love/trust/cuddle hormone is an oversimplified view of something complex that researchers are still working hard to understand better. Speaking of drugs like oxycontin, did you know that not only is oxytocin release at play when we cuddle, but that our endogenous opioid system is heavily involved in why cuddling feels good and rewarding?

    (Here's a blurb from a paper on endogenous opioids that gives you a better idea of what they are)
    "The endogenous opioid system is one of the most studied innate pain-relieving systems. This system consists of widely scattered neurons that produce three opioids: beta-endorphin, the met- and leu-enkephalins, and the dynorphins. These opioids act as neurotransmitters and neuromodulators at three major classes of receptors, termed mu, delta, and kappa, and produce analgesia. Like their endogenous counterparts, the opioid drugs, or opiates, act at these same receptors to produce both analgesia and undesirable side effects. This article examines some of the recent findings about the opioid system, including interactions with other neurotransmitters, the location and existence of receptor subtypes, and how this information drives the search for better analgesics. We also consider how an understanding of the opioid system affects clinical responses to opiate administration and what the future may hold for improved pain relief. The goal of this article is to assist clinicians to develop pharmacological interventions that better meet their patient's analgesic needs."

    Here's a blurb from a paper on cuddling and stress-buffering that touches on these two systems at play. I'll attach the links as well.

    "Opioid and oxytocin systems are distinct, but in many respects they can function in a convergent or overlapping manner in social interactions. Convergent effects include subjective hedonic feelings, mild painkilling properties, an influence on HPA and SAM axes, as well as the capacity for fine-tuned context-sensitivity via cortical top-down modulation. Each is tightly associated with affiliative behaviors, particularly those involving touch—for example, the petting, nudging, grooming, play-elicitation, and snuggling that often accompanies a reunion in many species."

    "The endogenous opioid system and clinical pain management"
    https://pubmed.ncbi.nlm.nih.gov/16082232/

    "Keep Calm and Cuddle on: Social Touch as a Stress Buffer"
    https://link.springer.com/article/10.1007/s40750-016-0052-x

  • BabichevBabichev
    edited October 2021

    Reducing oxytocin to the love hormone is a gross oversimplification. It’s also involved in an “us and them” mentality, increasing bonding within a group but also involved in increased aggression towards outsiders.

    As usual, the popular press misses all the nuances. Cortisol, for instance, is considered a marker for stress. However, it’s also necessary for certain functions and too little cortisol is just as bad as too much. When it comes to the biology of human behavior, nothing is simple.

    https://bigthink.com/videos/robert-sapolsky-us-vs-them-thinking-is-hardwired-but-theres-hope-for-us-yet/

  • NicoSnuggsNicoSnuggs

    Thank you for the sources you shared @Babichev and @calmcontact ;

    And I will have to check out that show you suggested @xandriarain ; It sounds fascinating.

  • Bella_SeraBella_Sera

    Wow, y’all stomped all over @xandriarain’s idea for a silly role play game.

  • MonkeyNeedsAHugMonkeyNeedsAHug
    edited October 2021

    @xandriarain,

    I appreciate the show recommendation and the lighthearted thought experiment suggested by peddling oxytocin irresponsibly instead of OxyContin.

    Thanks for sharing!

    🐒

  • CuddleDuncanCuddleDuncan Mod
    edited October 2021

    @BellaSera it's one of those 'laws' of the internet. No matter how obvious it is that something is a joke - including labelling it "this is a joke" - somebody will take it seriously. 🙄

  • calmcontactcalmcontact

    I do think @CharlesThePoet has a point - it does seem that some people already sort of exaggerate or conveniently simplify the role of oxytocin and its "benefits" when advertising their services.

    @xandriarain So sorry and not meaning to stomp on your post at all. I did understand it was meant to be a role play but got caught up in responding to some of the comments that were getting into the real biological impacts of different substances and/or neurotransmitters.

    Thank you for the show recommendation and your fun idea, sorry we ran away from the intended topic!

  • ShakeShake

    Hello. I'm a pleasant & soothing sounding voice over. Here to talk about our product while your tv screen focuses on random people doing mundane things, or maybe we'll show you their dog for some reason. Who cares? It's adorable and you love it.

    Life got ya down? Those long hours just aren't worth it anymore? Tired of antidepressants not quite doing the job for you? Well we can cure all that ills you with rich new Oxytocin. Oxytocin puts all other drugs to shame with guaranteed relaxation, random giggling, potential cameos from pets, and an all around soothing aura for you & your cuddle partner. Please consult your doctor to see if you are right for Oxytocin, and won't start hearing wedding bells after one session with a cuddlist. Oxytocin is an unregulated drug and is to be used at your own discretion.

    Cuddle Comfort. It's the touch you crave, and the sun to brighten your stormy day.

    Warning: sideeffectsmayincludehandsyenthusiastsselfproclaimedrealmenfromcleavlandohiounexpectedarousalunsolicitedpicsghostingnoshowsorallaroundbadhygienefromyourcuddlebuddynoneofwhichweareresponsiblefor

    Try Oxytocin today! 😃

  • Nature_Lover_Nature_Lover_

    @Shake49 way to knock or out of the park!!! 😁

    @xandriarain I am constantly buzzing on how good I feel after cuddles and often joke about the benefits - I’ve been known to say cuddling can improve your credit score and cure dandruff 😝🤷‍♀️

  • calmcontactcalmcontact

    @Shake49 That was amazing!!!! I'd love to see someone outdo that. Wow.

  • xandriarainxandriarain

    @Shake49 A+ that was awesome. You understood the assignment.

  • [Deleted User]ImajenMoon (deleted user)

    Hahahahaahahaha!!!! Way to go, @Shake49 ! Especially the long list of unintended, unexpected "side effects"!!! Hilarious!!! Like @xandriarain said, you understood the assignment!!! lololol!!!

  • GentleMan1111GentleMan1111

    Sadly it’s easier to get the former than the latter for many of us.

  • entwineentwine

    One of those threads where think this could be interesting... Then start slowly reaching for a face palm...with a slight tilt and nod of head for some useful links to resources...while hand still slowly reaching face, then, bOOm, pure delight that someone gets it.
    Don't think anyone can follow that up @Shake49. Your post was epic and was a wonderful read. Sure did make it all worth it.

    tl;dr great thread @xandriarain

  • ShakeShake

    Hahahaha, thanks guy's. Glad you enjoyed it! I've been in my fair share of RP's before & couldn't resist. ^.^
    And thank YOU @xandriarain for the thread. It was a fun idea to play with!

  • quixotic_lifequixotic_life

    @xandriarain ~ ding~dong big pharma calling...

    You may recall the article on WebMD from May of 2020 titled, "Health Benefits of Cuddling" where it was reported that, "A good cuddle may give you more than just moral support after an injury. The oxytocin it releases can help block pain signals. It works so well that doctors are trying to figure out how to treat people with a lab-made form of it."

    Well figure it out we did!! Oxytocininine RR (ORR- rapid release) and Oxytocininine XR (OXR -extended release) are just the breakthroughs we'd hoped for.

    Our trials in guinea pigs and gorillas found that ORR was effective at treating behaviors related to touch aversion and aggression. From shy trembling timidness to the pounding of one's chest, ORR has shown us the positive calming effects it has. It's a short burst of the 'good stuff' to help get one through, and be better able to access their 'happy place'.

    The benefits if OXR on the other hand, were best seen in our trials with horses and dogs. We found that over time, regular consumption of OXR put a giddy-up back in their step and worked wonders on those pathetically depressing puppy-eyes. No sad whinnies or whines around here. Neigh... Just happy tail flicks and wags.

    @xandriarain , as you are a reputable CC Pro, I'll be leaving you with these Oxytocininine samples, along with some nice swag. Not just mugs, pens and pads of paper, but a special ASMR cd with varied recordings of 'Oxytocininine' mixed with other sounds, for your clients to enjoy in your waiting room. Additionally, here are these handy 'Oxytocininine' branded toothbrushes and tooth paste tubes for those who need to freshen up first. And finally, to make their wait as comfy as can be, I'll be leaving these ultra soft 'Oxytocininine' hug pillows, lap blankets and foot rests so your clients can start to experience all the positive benefits of 'Oxytocininine' has to offer before you've even given them a sample.

    Thank you for your time & happy cuddles...

  • ShakeShake

    Well done Dr. @quixotic_life
    Your pharmacy will be recieving a complimentary gift basket, as well as a lovely pen for your desk. The pen has a sticker on it.

  • quixotic_lifequixotic_life

    @Shake49 ~ Sweet!! I love both pens AND stickers!! Winning!! 🙆‍♀️

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